Expression of bap Gene in Clinical Acinetobacter baumannii Isolates in Khorramabad, Iran
نویسندگان
چکیده
Background: Biofilm-associated protein (Bap) in Acinetobacter baumannii is an essential factor biofilm production and persistence the hospital environment. Objectives: This study aimed to detect bap gene A. by real-time polymerase chain reaction (PCR) from clinical specimens Khorramabad, Iran. Methods: cross-sectional was performed during April 2017 - 2018 on 43 strains samples collected identified microbiological biochemical tests. The expression of evaluated PCR. Data were analyzed with SPSS version 24. Results: Out strains, 23, 8, 3, 3 isolated chest sputum, wounds, urine, tissues, blood, and, respectively. According PCR results, all isolates had except one. Real-time showed significant differences between diverse samples. highest found sputum wound a difference other (P < 0.0001). Conclusions: We observed most high this Therefore, further studies are recommended find strategies inhibit formation, which help treat infections caused biofilm-forming strains.
منابع مشابه
Molecular Analysis and Expression of bap Gene in Biofilm-Forming Multi-Drug-Resistant Acinetobacter baumannii
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متن کاملMolecular Analysis and Expression of bap Gene in Biofilm-Forming Multi-Drug-Resistant Acinetobacter baumannii.
BACKGROUND Acinetobacter baumannii is commonly resistant to nearly all antibiotics due to presence of antibiotic resistance genes and biofilm formation. In this study we determined the presence of certain antibiotic-resistance genes associated with biofilm production and the influence of low iron concentration on expression of the biofilm-associated protein gene (bap) in development of biofilm ...
متن کاملmolecular analysis and expression of bap gene in biofilm-forming multi-drug-resistant acinetobacter baumannii
background: acinetobacter baumannii is commonly resistant to nearly all antibiotics due to presence of antibiotic resistance genes and biofilm formation. in this study we determined the presence of certain antibiotic-resistance genes associated with biofilm production and the influence of low iron concentration on expression of the biofilm-associated protein gene (bap) in development of biofilm...
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ژورنال
عنوان ژورنال: Gene, cell and tissue
سال: 2022
ISSN: ['2345-6833', '2345-6841']
DOI: https://doi.org/10.5812/gct-124061